In this article, Professor Vittorio Calabrese explains the role that the mushrooms Coriolus versicolor and Hericium erinaceus may play in inhibiting the progression of diseases related to oxidative stress such as dementia or early Alzheimer's disease. The role of this mushrooms comes from upregulating LXA4 a protein in the brain cells membrane that will stimulate certain systems within our body to reduce these oxidative species.

The aim of this study was to investigate the safety of the CV biomass form, as it is commonly used as a food supplement. The CV biomass powder was dissolved in distilled water and administered daily (2.5, 5.0, and 7.5 g/kg live weight) in single doses by gavage to both female and male Charles River albino rats.

There is a body of thought that viruses such as the herpes simplex virus (HSV-1) is a contributing factor in the development of Alzheimer´s disease. In addition, Dr LaFerla at the University of California has suggested the activation of Lipoxin A4 (LXA4) could reduce the progress of (or delay the onset of) Alzheimer´s disease. This article provides the rationale for the use of mushroom nutrition (in the form of a combination of Coriolus versicolor and Hericium erinaceus (biomass)), to provide both anti-viral protection and activation of LXA4.

(Jsilvacouto@netcabo.pt)

This poster was presented at the 14th World Congress of Cervical Pathology and Coloscopy, July 4-7, 2011 in Rio de Janeiro, Brazil

Conclusion: The use of Coriolus versicolor for one year revealed a great efficacy, whether in the regression of the displasia (LSIL) or in the disappearance of the High Risk HPV. It seems therefore, to be a very useful food supplementation with positive therapeutic impact, either in the reversion of LSIL (with High Risk HPV+), or in those HSIL patients, who have undergone surgery but experience continued High Risk HPV viral count.


1 Gynaecology Department-Portuguese Institute of Oncology-Cervical Pathology Unit, Coimbra, Portugal
2 CEF/Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

March 7th, at the 20th European Congress of Obstetrics and Gynaecology

This poster presents the results of a year long study on Coriolus versicolor supplementation in HPV patients with low-grade squamous intraepthithelial lesions (LSIL).

Download also the press release, click here

ESCVN/ ECVCN – 5 – 7th October 2006 - Nantes

This work was conducted with a mushroom (Coriolus versicolor) which is in the market for human and animal use. Mushroom polysaccharides, particularly ß-glucans, have antitumour and immunomodulating properties.

Archives of Environmental Health, August 2003 (Vol. 58 (No.8 )). Reprinted with permission of the Helen Dwight Reid Educational Foundation. Published by Heldref Publications, 1319 18th Street, NW, Washington, DC 20036-1802. Copyright � (2004).

In this article Dr. Monro points discusses how 20% of all cancers are triggered by viral infections. Dr. Monro outlines that having provided 30 Chronic Fatigue Syndrome patients Coriolus-MRL supplementation over eight weeks, there were significant improvements in the overall immune systems of the majority of the patients and that Coriolus supplementation could be utilized as a preventative immunutrition for those patients with such viral conditions that could develop into more serious oncological conditions i.e. HPV infection or Epstein Barr infection. Dr. Monro also outlines that Coriolus supplementation not only increases Natural Killer cell activity by 35%, but may also play a role in facilitating intercellular communication, thereby allowing the immune system to operate more effectively.

For more information on Heldref Publications and the Archives of Environmental Health, see the following link http://www.heldref.org

Presented at the 10th International Congress of Mucosal Immunology in Amsterdam, June 28th - July 1st, 1999.

This curiosity outlines the impact of Coriolus supplementation (6.0 grams per day to 9.0 grams per day) on the CD4 levels and viral load levels of three (3) Kaposi sarcoma patients. Results: For Kaposi sarcoma patients, Coriolus versicolor supplementation at 6.0 grams per day to 9.0 grams per day can significantly increase CD4 levels and provide a better quality of life.

To Contact Mr John Tindall please contact Yuan Clinic at:
Yuan Clinic
c/o Green Healer7 Clapham High Street
London SW4 7TS
United Kingdom

Tel/Fax:+44-207-622-9079.

In this case study on the use of Coriolus versicolor in fifteen (15) patients with Chronic Fatigue Syndrome, Dr. Monro measures the increase in Natural Killer Cell (NK) activity over 45 days when Coriolus supplementation is given at 3.0 grams for fifteen (15) days and then decreased to 1.5 grams for thirty (30) days. Results: Coriolus supplementation increased NK cell activity significantly in Chronic Fatigue Syndrome patients.

To contact Dr.Jean Monro at Breakspear Hospital

Tel:44-1442-261-333 / Fax:44-1442-266-388

Presented at the 4th International Symposium on Mushroom Nutrition, University of Westminster, June 15th, 2002.

Professor Lorite gives a Traditional Chinese Medicine (TCM) perspective on the reason that women having Chronic Fatigue Syndrome over a long period of time may suffer from breast lumps / myomas. She provides suggestions for treatment from a TCM perspective that includes acupuncture, herbs and Coriolus versicolor supplementation.

To contact Professor Nuria Lorite
Centro BilobaC/ Santa Clara, 4128200 San Lorenzo de El EscorialMadrid Spain

Tel.: +34 650 43 90 91

Email: nurialoriteayan@gmail.com

This study of increasing Coriolus versicolor supplementation (4.5 grams per day to 13.0 grams per day over a 90 day period) measures the impact of such supplementation on telomerase activity, interleukin 5, interleukin 12 and Tumour Necrosis Factor Beta over 120 days. Results were a significant decrease in teleomerase and interleukin-12 activity, followed by a significant increase in interleukin-5 activity within 120 days.

Presented at the 5th International Symposium on Mushroom Nutrition, University of Westminster, June 14th, 2002.